What does transfusion syndrome mean?

Jun 10, 2023 Source: Cainiu Health
Dr. Zhang Heyang
Introduction
Transfusion syndrome is a disease caused by adverse reactions occurring during blood transfusion. In general, symptoms of transfusion syndrome include fever, chills, chest pain, difficulty breathing, and hypotension, which can be fatal in severe cases. Once symptoms of transfusion syndrome appear, the transfusion should be stopped immediately, followed by appropriate examination and evaluation.

Transfusion syndrome is a disease caused by adverse reactions occurring during blood transfusion. The details are as follows:

In general, symptoms of transfusion syndrome include fever, chills, chest pain, dyspnea, hypotension, and in severe cases, it may lead to death. Once symptoms of transfusion syndrome appear, the transfusion should be stopped immediately, followed by appropriate examination and evaluation. If a transfusion reaction is confirmed, corresponding treatment measures must be taken. Transfusion syndrome may cause dysfunction in multiple organs; therefore, supportive therapy is required, including oxygen therapy and fluid resuscitation, to maintain the patient's vital signs and organ function. Transfusion syndrome is triggered by mediators such as histamine released during the transfusion process. Thus, antihistamine medications can be administered. Patients may take chlorpheniramine maleate tablets or promethazine hydrochloride tablets as prescribed to alleviate symptoms and control the condition. In cases of severe transfusion reactions, corticosteroids may be given. Patients can use medications such as methylprednisolone sodium succinate for injection or dexamethasone sodium phosphate injection according to medical instructions.

In summary, transfusion syndrome is a serious adverse reaction associated with blood transfusion and requires prompt diagnosis and treatment. Management of transfusion syndrome should be based on the patient's clinical condition and underlying causes to ensure patient safety. Additionally, to reduce the incidence of transfusion syndrome, healthcare providers should carefully select appropriate blood components and techniques during transfusion to enhance transfusion safety.

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