What are the clinical manifestations of Sweet's syndrome?
Sep 04, 2023
Source: Cainiu Health
Dr. Yang Shuwen
Introduction
In general, the clinical manifestations of Sweet's syndrome include fatigue, fever, sudden onset of skin lesions, leukocytosis, and vasodilation. Sweet's syndrome is characterized by painful, raised erythematous skin lesions caused by increased neutrophils infiltrating the superficial and mid-dermis, leading to symptoms such as fatigue in patients. If patients experience any discomfort, it is recommended that they seek timely medical attention at a hospital.
In general, the clinical manifestations of Sweet's syndrome include fatigue, fever, sudden-onset skin lesions, leukocytosis, and vasodilation. A detailed analysis is as follows:
1. Fatigue
Sweet's syndrome is characterized by painful, raised erythematous skin lesions caused by increased neutrophils infiltrating the superficial and middle layers of the dermis. Patients may experience fatigue. Treatment may include oral vitamin C tablets, vitamin E tablets, or other medications as directed by a physician.
2. Fever
Fever is common in patients with Sweet's syndrome, with body temperature often exceeding 38°C. The fever typically coincides with skin lesions and tends to last for an extended period. Medications such as prednisolone acetate tablets or acetaminophen tablets may be taken orally as prescribed.
3. Sudden Skin Lesions
The most typical feature of Sweet's syndrome is the sudden onset of symmetric erythematous plaques or nodules. These skin lesions are usually red or purplish-red, have well-defined borders, irregular shapes, and are often accompanied by significant swelling and pain. Topical treatments such as compound Sophora flavescens lotion or desonide cream may be used as directed by a physician.
4. Leukocytosis
Blood tests in patients with Sweet's syndrome may show elevated white blood cell counts, particularly neutrophilia. Treatment may include cefixime tablets, oseltamivir phosphate granules, or other medications as prescribed.
5. Vasodilation
Definitive diagnosis of Sweet's syndrome usually requires a biopsy of the affected skin. Histological examination reveals extensive neutrophilic infiltration in the epidermis and dermis, often accompanied by edema and vasodilation. Medications such as phentolamine mesylate tablets or prazosin hydrochloride tablets may be prescribed for treatment.
If patients experience any discomfort or symptoms, it is recommended to seek timely medical evaluation at a hospital to avoid delays in diagnosis and treatment.
