What tests can be done to determine if there is liver damage?

Mar 28, 2023 Source: Cainiu Health

Dr. Lu Haiying

Introduction

In general, liver function tests, coagulation function tests, liver ultrasound, liver biochemistry, and liver biopsy can help determine whether there is liver damage. These tests are typically performed based on the clinician's judgment. If you are concerned about your liver health or at risk for liver injury, please consult a doctor for evaluation and advice.

Generally, liver injury can be detected through tests such as liver function tests, coagulation function tests, liver ultrasound, liver biochemistry, and liver biopsy. The details are as follows:

1. Liver Function: Liver function is a key indicator reflecting whether the liver is damaged. When the liver is injured, markers of hepatocellular inflammation—such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST)—typically show significant elevation. In cases of severe liver damage, total bilirubin, indirect bilirubin, and direct bilirubin levels may also rise markedly.

2. Coagulation Function: Liver injury can also lead to abnormal coagulation function, as liver damage directly affects the production of clotting factors.

3. Liver Ultrasound: Liver ultrasound is a non-invasive imaging method that evaluates the size, structure, and any abnormalities of the liver using sound waves. It can help detect conditions such as fatty liver, tumors, or other structural issues.

4. Liver Biochemistry: This includes measuring levels of fats, bile acids, cholesterol, and other substances in the blood to assess liver function and fat metabolism.

5. Liver Biopsy: Liver biopsy involves taking a small sample of liver tissue for microscopic examination and is a diagnostic tool used to confirm liver injury. Although it is an invasive procedure, it provides detailed information about the type and severity of liver disease.

These tests are typically ordered based on the physician’s clinical judgment. If you are concerned about your liver health or at risk for liver damage, please consult a doctor for evaluation and recommendations.

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