Did you add the medication to the nebulizer?
Under normal circumstances, there is no need to cover the mouthpiece when using a standard mouthpiece or face mask after adding medication for nebulization. However, covering the mouthpiece may be required for specific types of nebulizers or if explicit operational instructions indicate so. If in doubt, it is recommended to consult a healthcare professional in advance. Detailed explanations are as follows:

If using a common household or medical compressive nebulizer, there is no need to cover the mouthpiece after adding medication when using either a mouthpiece (the patient holds the mouthpiece in their mouth) or a face mask (covering both mouth and nose). These nebulizers convert liquid medication into mist via airflow, which is then directly inhaled through the respiratory tract. An open configuration ensures smooth delivery of the mist into the lungs without affecting drug absorption.
However, if using a specific type of nebulizer (such as certain ultrasonic nebulizers that require closed operation), or if medical personnel explicitly instruct that the mouthpiece should be covered after adding medication, the nebulizer cap must be securely closed as directed. Such devices may require a sealed environment to maintain adequate mist concentration or prevent leakage and waste of medication. Failure to close the device properly may reduce nebulization efficiency and even prevent the medication from working effectively.
Before starting nebulization, confirm the nebulizer type and read the operating instructions carefully, then assemble the accessories correctly after adding medication. During nebulization, maintain a comfortable posture and avoid vigorous movement. After treatment, clean the nebulizer accessories promptly, air-dry them, and store for future use to prevent bacterial growth that could affect subsequent applications.