How are gallstones formed?

Sep 22, 2024 Source: Cainiu Health
Dr. Gao Jun
Introduction
Gallstones may be caused by factors such as genetic predisposition, hormonal changes, hemolytic anemia, biliary tract infections, and diabetes. To prevent gallstones, it is important to maintain a balanced diet, reduce intake of high-fat and high-cholesterol foods, increase dietary fiber and fluid intake, and maintain regular lifestyle habits along with appropriate physical exercise to promote overall health.

Under normal circumstances, gallstones may be caused by factors such as genetic predisposition, hormonal changes, hemolytic anemia, biliary tract infections, and diabetes. It is recommended to seek medical attention promptly and follow a doctor's guidance for treatment, including general management and medication. Specific analysis is as follows:

1. Genetic Factors

Individuals with a family history of gallstones have a higher risk of developing the condition. This may be related to inherited genes affecting cholesterol metabolism, bile composition, and gallbladder emptying function. Small gallstones may be naturally expelled from the body through urine by drinking plenty of water in daily life.

2. Hormonal Changes

Elevated estrogen levels, such as during pregnancy, can affect cholesterol metabolism and bile secretion, increasing the risk of gallstone formation. In daily life, reducing intake of high-fat and high-cholesterol foods can help improve this condition.

3. Hemolytic Anemia

Hemolytic anemia is usually associated with intrinsic abnormalities of red blood cells. This condition leads to elevated bilirubin levels; when excess bilirubin enters the bile, it alters bile composition, potentially causing the aforementioned symptoms. Patients may also experience fatigue, palpitations, and other symptoms. Treatment typically involves medications such as Danshitong Capsules, Danshu Soft Capsules, or Danshu Granules, as prescribed by a physician.

4. Biliary Tract Infection

Biliary tract infections may result from biliary obstruction or bacterial infection. Such infections can cause gallbladder wall edema and congestion, impairing bile excretion and concentration, thereby creating conditions favorable for stone formation. Symptoms may include jaundice and vomiting. Treatment under medical supervision may involve medications such as Cefoperazone Sodium for Injection, Penicillin V Potassium Tablets, or Xiaoyan Lidan Tablets.

5. Diabetes

Diabetes may be related to genetic factors, unhealthy lifestyles, or autoimmune conditions. Diabetic patients often suffer from hyperlipidemia and hyperinsulinemia, which promote cholesterol deposition in bile and contribute to gallstone formation. Symptoms may include increased appetite and weight loss. Medications such as Glibenclamide Tablets, Metformin Hydrochloride Tablets, or Acarbose Tablets should be used according to medical advice.

To prevent gallstones, it is important to maintain a balanced diet, reduce consumption of high-fat and high-cholesterol foods, increase dietary fiber and fluid intake, maintain regular lifestyle habits, and engage in appropriate physical exercise to promote overall health.