What causes low uric acid levels and what are the effects?
Sep 29, 2024
Source: Cainiu Health
Dr. Yang Guang
Introduction
Infections, genetic factors, and other conditions may trigger glomerulonephritis, leading to impaired kidney function and affecting uric acid excretion, which could result in low uric acid levels. Symptoms may include edema, abnormal urination, and loss of appetite. Medications such as cyclosporine soft capsules, furosemide tablets, and spironolactone tablets may be used under medical guidance to promote uric acid excretion. If any abnormalities occur, prompt medical attention is recommended.
Under normal circumstances, low uric acid levels may be caused by improper diet, genetics, medication effects, glomerulonephritis, cirrhosis, and other factors. If abnormalities occur, timely medical consultation is recommended. Specific analyses are as follows:
1. Improper Diet
Long-term fasting or maintaining a low-purine diet over an extended period—such as in vegetarians—may reduce uric acid production in the body. Low uric acid typically does not present obvious symptoms. It is recommended to adjust the dietary pattern by moderately increasing purine-rich foods such as meat and seafood to maintain uric acid levels within the normal range.
2. Genetics
An individual's genetic makeup may influence uric acid levels. Some people may naturally have a stronger ability to metabolize uric acid, leading to lower levels. Usually, no other discomfort occurs, but regular monitoring of uric acid levels is advised.
3. Medication Effects
Diuretics, chemotherapy drugs, and others may affect the kidney's reabsorption of uric acid, increasing its excretion and thereby lowering uric acid levels. There are usually no significant symptoms, although side effects related to the medication—such as electrolyte imbalances, nausea, and vomiting—may occur. It is recommended to adjust the dosage or switch medications according to specific conditions under medical guidance.
4. Glomerulonephritis
Glomerulonephritis may be triggered by infections, genetic factors, or others, causing kidney dysfunction that affects uric acid excretion, potentially resulting in low uric acid levels. Symptoms may include edema, abnormal urination, and loss of appetite. Medications such as cyclosporine soft capsules, furosemide tablets, and spironolactone tablets may be used as directed by a physician to promote uric acid excretion.
5. Cirrhosis
Cirrhosis results from long-term liver damage leading to fibrosis and structural changes, which disrupt the normal metabolic pathways of uric acid, causing reduced production or increased excretion. It may be accompanied by symptoms such as jaundice, ascites, and liver area pain. Doctors generally recommend hepatoprotective and diuretic medications such as compound glycyrrhizin tablets, liver-protecting tablets, and spironolactone tablets.
It is recommended to maintain a healthy lifestyle with regular作息 (daily routine), ensure sufficient sleep, improve dietary habits, regulate physical condition, and promote overall health.
