What are the causes of elevated lactate dehydrogenase?
Sep 30, 2024
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
In general, elevated lactate dehydrogenase (LDH) levels may be caused by factors such as growth and development phases, improper diet, excessive fatigue, myocarditis, or cirrhosis. It is recommended to seek medical attention promptly to determine the underlying cause and receive appropriate treatment. In daily life, one should maintain a light diet, engage in moderate exercise, ensure adequate sleep, and avoid excessive fatigue.
In general, elevated lactate dehydrogenase (LDH) levels may be caused by growth and development periods, improper diet, excessive fatigue, myocarditis, cirrhosis, or other reasons. It is recommended to seek medical attention promptly to determine the underlying cause and receive targeted treatment. Specific analyses are as follows:
1. Growth and Development Period
Infants, children, and adolescents may naturally have higher serum lactate dehydrogenase levels due to rapid physical development. Ensure adequate sleep and moderate exercise in daily life.
2. Improper Diet
Long-term or excessive intake of high-protein foods may increase protein metabolism in the body, leading to mildly elevated LDH levels. Adjust dietary habits by reducing consumption of high-protein and high-fat foods.
3. Excessive Fatigue
Intense exercise or prolonged physical labor can damage muscle cells, causing them to release lactate dehydrogenase into the bloodstream, thereby increasing serum LDH levels. Reduce intense physical activity and heavy labor, and schedule rest and exercise appropriately.
4. Myocarditis
Myocarditis occurs when cardiac muscle cells are infected by viruses or other pathogens, resulting in cell damage and LDH release. Symptoms may include chest pain and palpitations. Patients should be treated under medical guidance with medications such as ribavirin granules, creatine phosphate sodium for injection, and coenzyme Q10 capsules.
5. Cirrhosis
Cirrhosis is often caused by hepatitis B virus infection, leading to liver cell damage and the release of intracellular LDH into the blood, which elevates serum LDH levels. Symptoms may include fatigue and jaundice. Under medical advice, patients may use entecavir dispersible tablets, diammonium glycyrrhizinate enteric-coated capsules, and silybin capsules for treatment.
In daily life, it is important to maintain a light diet, engage in appropriate physical activity, ensure sufficient sleep, and avoid excessive fatigue.
