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What does it mean when the percentage of eosinophils is low?

Nov 05, 2024 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Bacterial infection may cause changes in the immune system, potentially leading to an increased total white blood cell count. However, eosinophils may be consumed during the immune response, resulting in a decreased percentage of eosinophils. This condition is often accompanied by symptoms such as cough and sputum production. It is recommended to follow medical advice and use medications such as amoxicillin capsules, clarithromycin capsules, and metronidazole tablets for treatment.

Under normal circumstances, a low percentage of eosinophils may be caused by intense physical exercise, stress response, bacterial infection, hypercortisolism (Cushing's syndrome), systemic lupus erythematosus, and other reasons. If discomfort occurs, timely medical consultation is recommended. Specific analysis is as follows:

1. Intense Exercise

During intense physical activity, the body's stress response increases, leading to elevated levels of hormones such as adrenaline and cortisol. This may suppress the production of eosinophils in the bone marrow, resulting in a decreased percentage of eosinophils. After rest and recovery, eosinophil counts typically return to normal naturally.

2. Stress Response

When the body is under stress conditions such as cold exposure or hunger, the sympathetic nervous system may become abnormally excited, causing increased secretion of adrenal cortical hormones. This can inhibit the release of eosinophils from the bone marrow, leading to a reduced eosinophil percentage. This type of decrease is usually temporary and tends to improve once the underlying triggers are resolved.

3. Bacterial Infection

Bacterial infections may alter immune system function, potentially increasing total white blood cell count while eosinophils are consumed during immune responses, thereby causing a lower percentage of eosinophils. Symptoms often include coughing and sputum production. It is recommended to follow medical advice and use medications such as amoxicillin capsules, clarithromycin capsules, or metronidazole tablets for treatment.

4. Hypercortisolism (Cushing's Syndrome)

Excessive fat deposition may contribute to hypercortisolism, and elevated cortisol levels can suppress eosinophil production, leading to a reduced eosinophil percentage. This condition is often accompanied by symptoms such as hypertension and increased fracture risk. Under physician guidance, medications such as dexamethasone tablets, ketoconazole cream, or acetic acid prednisone tablets may be used for treatment.

5. Systemic Lupus Erythematosus (SLE)

Dysfunction of the immune system may lead to systemic lupus erythematosus, which commonly presents with a decreased eosinophil percentage along with symptoms such as rashes and fever. Under a doctor’s direction, treatments may include prednisolone acetate tablets, dexamethasone tablets, or cyclosporine soft capsules.

In daily life, appropriate physical exercise can be beneficial to enhance physical strength and boost immune function.

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