What are the effects and benefits of Domperidone?

Nov 11, 2024 Source: Cainiu Health
Dr. Shen Yonghua
Introduction
Domperidone tablets, commonly known as Motilium, may have effects and benefits including improving indigestion, treating vomiting, enhancing gastrointestinal motility, promoting the healing of gastric ulcers, and reducing gastroesophageal acid reflux. In daily use, domperidone tablets should be taken according to medical instructions to ensure proper medication and avoid adverse reactions. Domperidone tablets possess antiemetic properties.

In general, "Motilium" refers to domperidone tablets, which may have the following effects and benefits: improving indigestion, treating vomiting, enhancing gastrointestinal motility, promoting healing of gastric ulcers, and reducing acid reflux. The details are as follows:

1. Improving indigestion

Domperidone tablets promote peristalsis of gastrointestinal smooth muscles, accelerating the digestion and absorption of food in the gastrointestinal tract. This helps relieve symptoms of indigestion caused by delayed gastric emptying or reduced gastrointestinal motility, such as bloating, belching, and nausea.

2. Treating vomiting

Domperidone has antiemetic effects, likely due to its ability to block both central and peripheral dopamine receptors. Dopamine is a neurotransmitter involved in triggering vomiting; by inhibiting its action, domperidone reduces the occurrence of vomiting reflexes.

3. Enhancing gastrointestinal motility

Domperidone acts directly on gastrointestinal smooth muscles, increasing their contractility and tone. This helps maintain normal gastrointestinal structure and function, preventing gastrointestinal relaxation and dysfunction caused by insufficient muscle tone.

4. Promoting healing of gastric ulcers

Domperidone reduces gastric acid secretion, thereby decreasing the erosive effect of acid on the gastric mucosa and creating a favorable environment for ulcer healing. Additionally, it enhances gastrointestinal motility, accelerating the repair and regeneration of gastric mucosal tissue, thus speeding up the healing process of gastric ulcers.

5. Reducing acid reflux

Domperidone increases the tone of the lower esophageal sphincter, preventing stomach contents from flowing back into the esophagus. It also reduces gastric acid secretion, minimizing irritation and damage to the esophageal mucosa caused by acid, thereby effectively reducing episodes of acid reflux.

In daily use, domperidone tablets should be taken according to medical advice to ensure proper medication and avoid adverse reactions.

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