What to do if progesterone levels are low in early pregnancy

In general, low progesterone levels during early pregnancy may be caused by differences in examination timing, individual variation, luteal insufficiency, adrenal cortical hyperfunction, or abnormal embryonic development. Improvement can be achieved through general treatment, medication, and other methods.

1. Variations in examination timing: Progesterone is secreted in a pulsatile manner, and its levels fluctuate at different times throughout the day. If testing happens to occur during a low point in progesterone secretion, the measured value may appear low. In such cases, multiple tests are recommended to comprehensively evaluate progesterone levels before taking further action.

2. Individual variation: Some women naturally have relatively lower baseline progesterone levels before pregnancy, but this does not necessarily indicate an adverse effect on embryonic development. If there are no abnormal symptoms or signs, special treatment generally is unnecessary, and regular prenatal checkups are sufficient.

3. Luteal insufficiency: After conception, the corpus luteum is responsible for progesterone secretion to support early embryonic development. If luteal function is suboptimal, progesterone production decreases. It is recommended to supplement progesterone under a physician's guidance using medications such as progesterone capsules or dydrogesterone tablets.

4. Adrenal cortical hyperfunction: Excessive secretion of adrenal corticosteroids due to adrenal cortical hyperfunction can inhibit progesterone synthesis and secretion. It is recommended to regulate adrenal cortical function under a physician's guidance using medications such as hydrocortisone tablets or betamethasone tablets.

5. Abnormal embryonic development: Chromosomal numerical or structural abnormalities in the embryo may affect the function of trophoblast cells, preventing normal progesterone secretion and resulting in decreased progesterone levels. It is recommended to supplement progesterone under a physician's guidance using medications such as medroxyprogesterone acetate tablets or vitamin E soft capsules, while closely monitoring embryonic development.

During early pregnancy, it is important to get plenty of rest, ensure adequate sleep, and avoid excessive fatigue and strenuous exercise. Regular prenatal checkups are necessary to monitor progesterone levels and embryonic development. Be attentive to any abnormalities such as abdominal pain or vaginal bleeding, and seek timely medical treatment if such symptoms occur.