What are the first-line medications for mycoplasma infection in children?
Generally, medications used to treat mycoplasma infection in children include Azithromycin Granules, Roxithromycin Granules, Clarithromycin Dispersible Tablets, Erythromycin Enteric-coated Tablets, and Ganmaoling Granules. Detailed explanations are as follows:
1. Azithromycin Granules: This medication demonstrates excellent antibacterial activity against mycoplasma and effectively inhibits the growth and proliferation of mycoplasma. Azithromycin, the active ingredient, achieves high tissue concentrations in the body, particularly exerting strong antibacterial effects at infection sites such as the respiratory tract.
2. Roxithromycin Granules: This medication has good lipid solubility, is rapidly absorbed after oral administration, and has high bioavailability, enabling it to quickly reach effective drug concentrations in the body and exert antibacterial effects. It effectively alleviates respiratory symptoms caused by mycoplasma infection in children, such as coughing and phlegm production, and has relatively mild side effects.
3. Clarithromycin Dispersible Tablets: This medication has strong antibacterial activity with a low minimum inhibitory concentration (MIC) against mycoplasma. It can exert antibacterial effects even at low drug concentrations and effectively reduces inflammation caused by mycoplasma infection.
4. Erythromycin Enteric-coated Tablets: This medication inhibits the synthesis of mycoplasma proteins, thereby achieving antibacterial effects. It demonstrates good efficacy against mycoplasma infection and causes relatively less gastrointestinal irritation compared to erythromycin, making it more acceptable to children.
5. Ganmaoling Granules: When children with mycoplasma infection also experience symptoms resembling the common cold, such as fever, headache, and nasal congestion, this medication can be used as an adjunct to relieve discomfort symptoms.
During mycoplasma infection in children, adequate rest should be ensured to facilitate recovery. Family members should closely monitor any changes in the child's condition. If symptoms such as persistent fever or worsening cough occur, timely follow-up and treatment are necessary.