Is the solution used in COVID-19 antigen tests toxic?
Dec 10, 2025
Source: Cainiu Health
Dr. Ren Yi
Introduction
Under normal circumstances, the components of the COVID-19 antigen test solution are non-toxic, but oral ingestion is not recommended. The test solution should be stored out of reach of children and pets to prevent accidental ingestion. If a small amount is accidentally swallowed, drink plenty of water immediately to help flush out the components, and closely monitor for any physical reactions. Test kits and related supplies should be properly organized and stored separately from food, medications, and other similar items.
Under normal circumstances, the components of the COVID-19 antigen test solution are non-toxic, but oral ingestion is not recommended. The detailed explanation is as follows:
The COVID-19 antigen test solution primarily contains buffer solutions, surfactants, and similar ingredients. Although it does not include added toxic substances, it is specifically designed for in vitro antigen testing and is not intended for absorption or metabolism by the human digestive system. If ingested orally, these components may irritate the oral mucosa, esophagus, and gastrointestinal tract, causing discomfort such as nausea, vomiting, and abdominal pain. Moreover, the solution's components cannot perform their intended testing function inside the body and instead increase the metabolic burden. Ingesting a large amount may lead to more significant adverse effects on the digestive system.
When using the test solution, store it out of reach of children and pets to prevent accidental ingestion. If a small amount is accidentally swallowed, immediately drink plenty of water to help flush out the components and closely monitor for any physical reactions. For daily storage, keep all testing supplies properly organized and strictly separated from food and medications. After use, promptly seal the packaging and dispose of it appropriately to maintain a clean and orderly living environment.
