What are the efficacy and effects of Ketotifen tablets?

Generally speaking, Ketotifen tablets refer to Ketotifen fumarate tablets. The functions and effects of Ketotifen fumarate tablets include anti-allergy, anti-asthma, anti-pruritus, cough suppression, and improvement of sleep quality, among others. Detailed explanations are as follows:

1. Anti-Allergy

Ketotifen fumarate tablets are antihistamine medications that effectively antagonize histamine H1 receptors. When the body is exposed to allergens such as pollen, dust mites, or animal fur, an allergic reaction may occur, causing a large release of histamine, which can lead to symptoms such as skin itching, swelling, sneezing, and runny nose. Ketotifen fumarate tablets can prevent histamine from binding to its receptors, thereby alleviating allergic symptoms.

2. Anti-Asthma

This medication can inhibit the release of allergic mediators and thus has certain preventive and therapeutic effects on asthma. During an asthma attack, mast cells release various inflammatory mediators, such as histamine and leukotrienes, causing airway smooth muscle contraction, increased mucus secretion, and inflammatory cell infiltration, which leads to airway narrowing and difficulty breathing. Ketotifen fumarate tablets can stabilize the mast cell membrane, reduce the release of these inflammatory mediators, lower airway hyperresponsiveness, and alleviate asthma symptoms.

3. Anti-Pruritus

Ketotifen fumarate tablets can relieve skin itching caused by allergies. Whether due to contact dermatitis, urticaria, or other allergic skin diseases, when itching occurs, Ketotifen fumarate can alleviate the sensation of itching through its antihistamine effects. Histamine is one of the key mediators causing skin itching, and by inhibiting histamine's effects, this medication can reduce itching to some extent and improve patient comfort.

4. Cough Suppression

Ketotifen fumarate tablets can reduce the excitability of the cough center and suppress the cough reflex, thereby exerting a cough-suppressing effect. Patients with allergic cough may experience persistent coughing, and taking Ketotifen fumarate tablets can help relieve coughing.

5. Improvement of Sleep Quality

Some patients may experience improved sleep quality after taking Ketotifen fumarate tablets. This is because allergic symptoms such as itching, nasal congestion, and coughing may interfere with sleep, and this medication alleviates allergic symptoms, indirectly helping patients fall asleep. Additionally, Ketotifen fumarate has a certain sedative effect, as it can inhibit the excitability of the central nervous system, making it easier for patients to enter deep sleep at night and reducing nighttime awakenings.

When using Ketotifen tablets, patients should follow their doctor's instructions, avoiding self-adjustment of dosage or discontinuation of the medication to ensure safe and effective control of allergic symptoms.