Which has fewer side effects, Tadalafil or Sildenafil?
Nov 08, 2024
Source: Cainiu Health
Dr. Cao Zhiqiang
Introduction
Both tadalafil and sildenafil are commonly available in tablet form. Generally, tadalafil may have relatively fewer side effects. However, individual variation in drug side effects typically exists. Compared with tadalafil, sildenafil may have a higher likelihood and severity of side effects. When selecting a medication, patients should fully consider their own condition and health status, and make decisions under the guidance of a physician.
Tadalafil and sildenafil are both commonly available in tablet form. Generally, tadalafil may have relatively fewer side effects. However, individual responses to drug side effects can vary significantly. A detailed comparison is as follows:
Tadalafil may cause side effects such as indigestion, migraine, arrhythmia, blurred vision, cough, and nosebleeds. These side effects are generally mild and typically resolve after discontinuation of the medication for a certain period.
Sildenafil can similarly cause side effects including headache, indigestion, and rash. Additional adverse reactions may include facial flushing, dizziness, insomnia, anxiety, and nausea. Long-term use of sildenafil may lead to drug dependence and potentially affect male fertility. Compared with tadalafil, sildenafil may have a higher likelihood and greater severity of side effects.
However, tadalafil remains in the body for a longer duration and requires approximately 144 hours to be completely eliminated. In comparison, sildenafil and its metabolites are cleared from the body within about 16 hours. This means that the side effects of sildenafil may be relatively short-lived and more easily metabolized and excreted by the body.
When choosing a medication, patients should fully consider their own health status and medical condition, and make decisions under the guidance of a physician.
