What are the efficacy and functions of Metaraminol Bitartrate Injection?
Nov 11, 2024
Source: Cainiu Health
Dr. Yang Shuwen
Introduction
Metaraminol Bitartrate Injection is a vasoactive agent that has the effects and functions of increasing blood pressure, improving circulating blood volume, enhancing cardiac contractility, alleviating shock symptoms, and improving tissue perfusion. When using Metaraminol Bitartrate Injection, it is necessary to closely monitor changes in the patient's heart rate and blood pressure to avoid adverse reactions caused by excessive elevation of blood pressure.
Metaraminol bitartrate injection is a vasoactive agent that functions to elevate blood pressure, improve circulating blood volume, enhance myocardial contractility, alleviate symptoms of shock, and improve tissue perfusion. Detailed mechanisms are as follows:
1. Elevating blood pressure: By directly stimulating adrenergic receptors, particularly the α1 receptors, it induces peripheral vasoconstriction, increases venous return, and thereby raises arterial blood pressure.
2. Improving circulating blood volume: It constricts peripheral blood vessels, reduces peripheral vascular resistance, and promotes blood return to the heart, thus improving circulating blood volume. Additionally, by increasing venous return, it helps enhance cardiac output, further improving circulation.
3. Enhancing myocardial contractility: It increases intracellular calcium concentration in myocardial cells, indirectly leading to enhanced myocardial contractility.
4. Alleviating symptoms of shock: Through its effects of elevating blood pressure, improving circulating blood volume, and enhancing myocardial contractility, metaraminol bitartrate can effectively relieve symptoms caused by various types of shock, such as hypotension and tachycardia.
5. Improving tissue perfusion: By constricting peripheral blood vessels and increasing blood pressure, it ensures blood supply to vital organs, thereby improving tissue perfusion. This helps reduce organ damage caused by shock and protects organ function.
During the use of metaraminol bitartrate injection, close monitoring of the patient's heart rate and blood pressure changes is necessary to avoid adverse reactions caused by excessive elevation of blood pressure. Additionally, this medication is contraindicated in patients allergic to it, and should be used with caution in individuals with a history of hypersensitivity.
