Can Hepatitis B "Big Three Positive" Turn Negative?

Dec 21, 2024 Source: Cainiu Health
Dr. Gao Jun
Introduction
In general, "big three positives" of hepatitis B refers to a type of viral hepatitis B infection, which is currently difficult to turn negative. However, for patients who are asymptomatic and have normal liver function, observation without specific treatment may be appropriate. For those patients with symptoms and abnormal liver function, timely treatment and regular follow-up are necessary in order to monitor disease progression and treatment response promptly.

Generally speaking, "Big Three Positive" refers to the "Big Three Positive" of hepatitis B. Currently, it is very difficult for the "Big Three Positive" of hepatitis B to become negative. If discomfort occurs, timely medical consultation is recommended. Detailed analysis is as follows:

The "Big Three Positive" of hepatitis B refers to the positivity of three markers: hepatitis B surface antigen, hepatitis B e antigen, and hepatitis B core antibody. This indicates that the virus in the body is currently active and may be replicating. At present, these positive markers cannot be converted to negative through treatment, therefore, "Big Three Positive" generally does not become negative.

However, if a patient with hepatitis B "Big Three Positive" is asymptomatic and has normal liver function, observation without specific treatment may be appropriate. For patients with symptoms and abnormal liver function, timely treatment according to medical advice with medications such as compound glycyrrhizinic acid for injection, glutathione for injection, and Huganning tablets may be necessary.

If identified as a carrier of hepatitis B "Big Three Positive," regular check-ups are necessary to monitor recovery and disease progression promptly, and adjust the treatment plan based on viral load. At the same time, maintaining good dietary and lifestyle habits is important to reduce liver damage.

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