Can Telmisartan and Amlodipine Besylate Tablets be used together?
Dec 23, 2024
Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Under normal circumstances, the dosage forms of Telmisartan include tablets and capsules. It is an angiotensin II receptor antagonist. Amlodipine Besylate Tablets belong to calcium channel antagonists and are commonly used in the treatment of hypertension. Telmisartan and Amlodipine Besylate Tablets can usually be used together. During use, patients should pay attention to adjusting their lifestyle, such as following a low-salt and low-fat diet and engaging in appropriate exercise.
Generally, telmisartan is available in tablet and capsule forms and is an angiotensin II receptor antagonist. Amlodipine besylate tablets belong to the class of calcium channel antagonists and are commonly used in the treatment of hypertension. Telmisartan and amlodipine besylate tablets can usually be used together. A detailed explanation is as follows:
Telmisartan, an angiotensin II receptor antagonist, primarily works by selectively blocking the binding of angiotensin II to receptor type 1, thereby relaxing vascular smooth muscle, reducing peripheral vascular resistance, and lowering blood pressure. It also offers certain benefits in improving ventricular remodeling. Amlodipine besylate tablets are calcium channel blockers that prevent calcium ions from entering vascular smooth muscle cells and cardiac muscle cells, causing vascular smooth muscle relaxation, decreasing peripheral vascular resistance, and subsequently lowering blood pressure. Additionally, it dilates the coronary arteries, improving myocardial blood supply.
When these two medications are used in combination, they exert antihypertensive effects through different mechanisms, synergistically lowering blood pressure. This combination therapy is an effective treatment option for hypertensive patients whose blood pressure is not adequately controlled with monotherapy. Moreover, combining these medications may offer certain advantages in reducing adverse effects. When used concomitantly with telmisartan, side effects may potentially be mitigated by the effects of telmisartan.
During treatment, patients should pay attention to lifestyle modifications, such as adopting a low-salt, low-fat diet, engaging in appropriate physical activity, quitting smoking, and limiting alcohol consumption. Following medical advice regarding medication use and monitoring is helpful in controlling blood pressure and reducing the complications associated with hypertension.
