Can I get a nucleic acid test immediately after receiving the third dose of the HPV vaccine?

Jun 09, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
The HPV vaccine, or human papillomavirus vaccine, generally allows for immediate nucleic acid testing after receiving the third dose of the vaccine. If necessary, this should be done under a doctor's guidance. The mechanisms of action of the human papillomavirus vaccine and nucleic acid testing are different, and they do not interfere with each other. The human papillomavirus vaccine is a preventive vaccine targeting the human papillomavirus.

HPV vaccine, namely human papillomavirus vaccine, generally allows for immediate nucleic acid testing after receiving the third dose. If necessary, it should be conducted under a doctor's guidance. Detailed analysis is as follows:

The mechanisms of action of the human papillomavirus vaccine and nucleic acid testing differ and do not interfere with each other. The human papillomavirus vaccine is a preventive vaccine targeting the human papillomavirus, primarily stimulating the body to produce antibodies to prevent diseases such as cervical cancer and penile cancer. In contrast, nucleic acid testing involves collecting samples such as respiratory secretions or feces to detect the presence of specific viral genetic material in the sample, determining whether an individual is infected with the virus. Since the human papillomavirus vaccine and nucleic acid testing target different viral components and stages of infection, they do not interfere with each other.

The core component of the human papillomavirus vaccine is protein, which differs from the viral genetic material detected by nucleic acid testing. The human papillomavirus vaccine mainly contains partial antigenic proteins of the virus; these proteins are recognized by the immune system upon entering the body, prompting the production of antibodies. Nucleic acid testing, however, identifies the presence of infection by detecting the virus's RNA or DNA. Due to the different targets of these two tests, receiving the human papillomavirus vaccine does not affect the accuracy of nucleic acid testing.

After vaccination, one should rest appropriately and avoid strenuous exercise to promote bodily recovery. It is also important to keep the injection site clean and dry, avoiding contact with water to prevent infection.

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