Does AIDS cause a decrease or increase in white blood cells?
Generally speaking, whether white blood cells increase or decrease in AIDS needs to be determined according to specific circumstances. If it is in the early stage of AIDS, white blood cells typically increase; however, in the middle to late stages, white blood cells may decrease. If experiencing any discomfort, timely medical consultation is recommended. Detailed analysis is as follows:
If it is in the early stage of AIDS, white blood cells usually increase. This is because the HIV virus mainly attacks CD4+ T lymphocytes in the human immune system. As the virus continues to replicate, the body's immune system initiates a defense mechanism. White blood cells, as immune cells, proliferate significantly and gather at the site of infection to fight pathogens, leading to an elevated white blood cell count.
However, in the middle to late stages of AIDS, white blood cells may decrease. White blood cell production and function depend on a normal immune environment. In the middle to late stages of AIDS, the disease has stronger destructive power, damaging the immune system, interfering with the hematopoietic microenvironment, and causing abnormal differentiation and proliferation of bone marrow hematopoietic stem cells, thereby reducing white blood cell production.
Patients are advised to maintain good living habits and mindset, undergo regular physical examinations and treatment under a doctor's guidance, to improve quality of life and prolong survival time.