What does it mean when the endometrial echo is uneven?
Endometrial echogenicity heterogeneity refers to a phenomenon observed during ultrasound examination where the endometrial image presents inhomogeneous changes. Detailed analysis is as follows:

If endometrial echogenicity heterogeneity occurs around menstruation or during the ovulatory period, and there are no symptoms such as abnormal vaginal bleeding or abdominal pain, it is often a physiological manifestation. Endometrial thickening before menstruation may lead to uneven echogenicity, and differences in localized endometrial proliferation during the ovulatory period can also cause this phenomenon. This condition typically resolves spontaneously with the menstrual cycle and does not require special treatment. A follow-up ultrasound after the menstrual period can be performed to confirm resolution.
When endometrial echogenicity heterogeneity is accompanied by abnormal uterine bleeding, abdominal pain, or infertility, it may be caused by pathological factors. Common causes include endometrial polyps, submucosal fibroids, endometrial hyperplasia, inflammation, or adhesions. For example, endometrial polyps may cause localized endometrial thickening and increased echogenicity, while endometrial hyperplasia may lead to diffuse echogenicity heterogeneity. In such cases, further diagnostic procedures such as hysteroscopy or diagnostic curettage are required to determine the underlying cause, followed by targeted treatment, such as polypectomy.
There is no need to panic upon finding endometrial echogenicity heterogeneity. First, clarify the phase of the menstrual cycle during the examination, follow medical advice to schedule follow-up ultrasounds at appropriate times, or undergo further investigations. If abnormal symptoms occur, seek timely medical attention. Maintain good reproductive health, avoid unnecessary intrauterine procedures, and reduce the risk of infection in daily life.