What does it mean to have thickened endometrium?

Jul 03, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In a normal menstrual cycle, the endometrium undergoes cyclical changes under the influence of estrogen and progesterone. The proliferative endometrium can thicken to 8-10 millimeters, and during the secretory phase, it can reach 10-14 millimeters. If the endometrium remains thicker than 5 millimeters after menstruation, or is accompanied by abnormal vaginal bleeding, menstrual irregularities, postmenopausal bleeding, or similar symptoms, it may indicate pathological thickening.

Normally, endometrial thickening refers to a condition where the endometrium exceeds the normal thickness range during ultrasound examination, caused by either physiological or pathological factors leading to abnormal endometrial hyperplasia. Detailed analysis is as follows:

During a normal menstrual cycle, the endometrium undergoes cyclical changes under the influence of estrogen and progesterone. During the proliferative phase, the endometrium can thicken to 8-10 mm, and during the secretory phase, it can reach 10-14 mm. If the endometrium remains thicker than 5 mm after menstruation or is accompanied by symptoms such as abnormal vaginal bleeding, menstrual disorders, or postmenopausal bleeding, it may indicate pathological thickening.

Physiological thickening is often related to the menstrual cycle and generally requires no special treatment. Pathological thickening commonly occurs due to excessive estrogen levels, endometrial polyps, endometrial hyperplasia, endometrial cancer, and other conditions. Diagnosis typically requires hysteroscopy or diagnostic curettage to obtain tissue samples for pathological evaluation, after which drug therapy or surgical treatment may be recommended based on the findings.

If endometrial thickening is detected, timely medical consultation is advised. Evaluation should include consideration of the menstrual cycle and associated symptoms to identify the underlying cause, followed by appropriate treatment as directed by a physician. It is also important to regulate hormone levels in daily life, avoid prolonged estrogen stimulation, and undergo regular gynecological examinations.

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