What is the normal reference range for uric acid?

Jul 08, 2025 Source: Cainiu Health

Dr. Yang Tiesheng

Introduction

The normal uric acid range for adult males should not exceed 420 μmol/L. This value is determined based on factors such as adult male hormone levels and metabolic characteristics. Daily diet, physical activity, and other factors may cause temporary fluctuations in uric acid levels, but persistent levels above this value are considered abnormal. In adult females, the normal uric acid level generally does not exceed 360 μmol/L.

Under normal circumstances, the standard for normal uric acid levels differs by gender. For males, the level generally does not exceed 420 μmol/L, while for females, it generally does not exceed 360 μmol/L. If abnormalities are detected, timely medical consultation is recommended. Detailed explanations are as follows:

The normal range for male uric acid should not exceed 420 μmol/L. This value is based on factors such as adult male hormone levels and metabolic characteristics. Daily diet and exercise may cause temporary fluctuations in uric acid levels, but consistently exceeding this value is considered abnormal.

The normal range for female uric acid levels is relatively lower, not exceeding 360 μmol/L, primarily due to the influence of estrogen on uric acid metabolism. Postmenopausal women may have a normal uric acid range closer to that of males due to decreased estrogen levels.

Uric acid levels should be assessed according to gender. Regular monitoring can help detect abnormalities in a timely manner. Maintaining a low-purine diet and adequate hydration in daily life helps keep uric acid within the normal range.

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