Can contraceptive pills cause blood clots?

Jul 31, 2025 Source: Cainiu Health

Dr. Zhang Lu

Introduction

If long-term continuous use of contraceptive pills containing high-dose estrogen is accompanied by conditions such as obesity, smoking, or a family history of thrombosis, blood coagulability may increase, leading to symptoms such as leg swelling and pain, which could indicate the formation of a blood clot. However, if the contraceptive pill contains a low dose of estrogen and is used for a short duration, and if there are no risk factors for thrombosis such as obesity or hypertension, then the likelihood of developing blood clots is significantly lower.

Generally, long-term use of contraceptives containing high-dose estrogen combined with existing thrombosis risk factors may lead to blood clots. However, short-term use of low-dose contraceptives with good overall health does not necessarily result in thrombosis. If you have concerns, it is recommended to consult a healthcare professional in advance. Detailed explanation is as follows:

If high-dose estrogen contraceptives are taken continuously over a long period and conditions such as obesity, smoking, or a family history of thrombosis exist, blood coagulability may increase, potentially causing symptoms like leg swelling and pain, which could lead to thrombosis.

If low-dose estrogen contraceptives are used for a short duration and there are no thrombosis risk factors such as obesity or hypertension, and no abnormal discomfort in limbs occurs, thrombosis is less likely.

During contraceptive use, monitor bodily changes, maintain moderate exercise, and avoid prolonged sitting. If symptoms such as leg pain or swelling, or shortness of breath occur, seek medical attention promptly to determine if they are related to thrombosis.

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