Can cephalosporin antibiotics be consumed together with durian?

Generally, cephalosporin antibiotics and durian are not recommended to be consumed together. However, if there is a sufficiently long interval between their consumption and no specific contraindications exist, durian may be consumed after evaluation by a physician. Detailed explanations are as follows:

If durian is consumed while taking cephalosporin antibiotics, certain components in durian may interfere with drug metabolism, increasing the likelihood of adverse reactions such as increased heart rate and facial flushing. In such cases, they should not be consumed together and must be strictly separated in time.

If at least five days have passed after completing a course of cephalosporin antibiotics, and there is no allergic reaction to either the medication or durian, and a physician confirms that the medication has been completely metabolized, eating durian typically does not cause adverse interactions and may be acceptable in moderation, although any bodily reactions should be closely monitored.

During the period of taking cephalosporin antibiotics, special attention should be paid to dietary combinations, avoiding consumption of durian shortly before or after taking the medication. If accidental co-consumption leads to adverse symptoms, eating should be stopped immediately and medical attention sought promptly; self-treatment is not advised.