Is there a significant difference between Dydrogesterone tablets and Progesterone?
Aug 21, 2025
Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, there are significant differences between Dydrogesterone Tablets and progesterone, primarily体现在成分、吸收代谢、适用情况等方面, specifically requiring selection under medical guidance based on individual needs. Although both belong to progestin medications, they differ明显 in dosage form, metabolic characteristics, and indications, and therefore should not be substituted arbitrarily. In daily life, medication should strictly follow medical instructions.
(Note: The final English translation should read smoothly and professionally, so here is the edited version based on the initial translation.)
Under normal circumstances, Dydrogesterone Tablets and progesterone have significant differences, mainly in their composition, absorption and metabolism, and indications. The specific choice should be made under a doctor's guidance according to individual needs. Although both are progestin medications, they differ notably in dosage form, metabolic characteristics, and clinical applications, and therefore should not be used interchangeably without medical advice. In daily use, it is essential to strictly follow the physician's instructions for medication.
Generally, there are significant differences between Dydrogesterone Tablets and progesterone, mainly reflected in their composition, absorption and metabolism, and clinical applications. The specific choice should be based on individual needs and made under a physician's guidance. Detailed analysis is as follows:
Dydrogesterone Tablets are a synthetic progestogen with a structure similar to natural progesterone. After oral administration, it is stably absorbed and not easily metabolized into other active products, resulting in relatively fewer side effects. It is commonly used in the treatment of dysmenorrhea, endometriosis, threatened abortion, and is especially suitable for individuals intolerant to natural progesterone.
Progesterone includes both natural and synthetic types. Natural progesterone is mostly available as injections or capsules, with components identical to the progesterone naturally secreted in the human body. It takes effect directly after injection, while oral formulations are easily metabolized by the liver, resulting in lower bioavailability. Synthetic progesterone generally has more noticeable side effects. Progesterone is mainly used for fetal preservation in threatened abortion, treatment of amenorrhea, luteal support in assisted reproduction, and injectable forms are more suitable for situations requiring rapid elevation of progesterone levels.
Although both belong to the class of progestogens, they differ significantly in formulation types, metabolic characteristics, and indications, and should not be substituted arbitrarily. In daily life, medication should strictly follow medical instructions, with regular follow-up testing of hormone levels. Dosage adjustments should not be made without authorization to ensure safe and effective drug use.
