What is the best medication for benign prostatic hyperplasia (BPH)?
Aug 28, 2025
Source: Cainiu Health
Dr. Cao Zhiqiang
Introduction
In general, there is no definitive answer to the question "what is the best medicine for treating benign prostatic hyperplasia (BPH)." Benign prostatic hyperplasia is a common condition in middle-aged and elderly men, caused by the enlargement of prostate tissue that compresses the urethra. Patients may take medications such as tamsulosin hydrochloride sustained-release capsules, finasteride tablets, epristeride tablets, tolterodine tartrate tablets, or saw palmetto fruit extract soft capsules, as directed by a physician.
Generally speaking, there is no such thing as "which medication is best for prostate enlargement." Benign prostatic hyperplasia (BPH) is a common condition in middle-aged and elderly men, caused by the enlargement of prostate tissue that compresses the urethra. Patients may use medications such as tamsulosin hydrochloride sustained-release capsules, finasteride tablets, epristeride tablets, tolterodine tartrate tablets, and saw palmetto fruit extract soft capsules under medical guidance. Detailed explanations are as follows:
1. Tamsulosin Hydrochloride Sustained-Release Capsules
Tamsulosin hydrochloride sustained-release capsules belong to α1-adrenergic receptor blockers, which selectively relax the smooth muscles of the prostate and bladder neck, alleviating urethral obstruction and improving symptoms of difficult urination. The medication should be swallowed whole without chewing or breaking the capsule. It is suitable for patients with mild to moderate BPH, especially those experiencing difficulty urinating or a weakened urine stream.
2. Finasteride Tablets
Finasteride tablets belong to 5α-reductase inhibitors. They work by inhibiting the conversion of testosterone into dihydrotestosterone, thereby reducing prostate volume and relieving urethral compression. Noticeable effects typically appear after continuous use for 3-6 months. This medication is suitable for patients with a larger prostate volume and can slow disease progression when taken long-term.
3. Epristeride Tablets
Epristeride tablets are also 5α-reductase inhibitors, with a mechanism of action similar to finasteride. They inhibit the production of dihydrotestosterone, reduce prostate volume, and improve urinary symptoms. This medication acts relatively quickly; some patients may experience symptom relief after taking it for 1-2 months. It is suitable for patients with poor tolerance to finasteride.
4. Tolterodine Tartrate Tablets
Tolterodine tartrate tablets belong to anticholinergic drugs. They block M receptors in the bladder's smooth muscles, inhibiting excessive bladder contractions and reducing symptoms such as frequent urination, urgency, and incontinence. This medication is suitable for patients with BPH combined with overactive bladder. Dry mouth and blurred vision are possible adverse effects to be aware of during treatment.
5. Saw Palmetto Fruit Extract Soft Capsules
Saw palmetto fruit extract soft capsules are plant-based preparations. They alleviate urinary discomfort caused by prostate enlargement by inhibiting prostate cell proliferation and reducing inflammation. This medication has high safety and few adverse reactions. It is suitable for patients with mild to moderate BPH or as an adjunct to conventional drug therapy.
Maintaining healthy lifestyle habits is important. Avoid prolonged sitting or standing, reduce urine retention, and maintain daily water intake between 1500-2000 milliliters. Eat a light diet and avoid spicy, stimulating, or greasy foods such as chili peppers and fried foods. Regular prostate ultrasound follow-ups are also necessary to monitor disease progression.
