What is ankylosing spondylitis?

Generally, ankylosing spondylitis is a chronic inflammatory disease primarily affecting the spine and sacroiliac joints, and it belongs to the group of seronegative spondyloarthropathies. A detailed analysis is as follows:

Ankylosing spondylitis is a chronic inflammatory disease associated with genetic and immune abnormalities, primarily involving the sacroiliac joints, spine, and surrounding joints. After onset, inflammation continuously damages joint cartilage and ligaments, leading to gradual calcification and stiffness of the joints. As the disease progresses, spinal rigidity and deformity may develop, often accompanied by symptoms such as low back pain and morning stiffness. Symptoms may temporarily improve with activity, but without timely control, spinal mobility may progressively deteriorate, potentially affecting peripheral joints such as the hips and knees. Some patients may also experience extra-articular manifestations, including involvement of the eyes, lungs, and other organs.

Once diagnosed with ankylosing spondylitis, it is important to start standardized treatment promptly to avoid delays that could lead to irreversible joint damage. Daily attention should be given to spinal protection, avoiding slouching or maintaining the same posture for prolonged periods. A mattress of moderate firmness is recommended to reduce stress on the spine. During exercise, strenuous or contact activities should be avoided, with priority given to low-impact activities such as walking, yoga, and swimming. These activities can help relieve stiffness while maintaining joint mobility. Regular follow-up assessments of inflammatory markers and spinal imaging are also necessary to dynamically adjust the treatment plan.