What are the side effects of aspirin?
Common formulations of aspirin include tablets and capsules. Generally, the main side effects of aspirin include gastrointestinal discomfort, bleeding tendency, allergic reactions, liver and kidney function damage, and salicylism. Detailed analysis is as follows:
1. Gastrointestinal Discomfort
Aspirin inhibits the synthesis of gastric mucosal protective factors and irritates the gastric mucosa. In individuals with sensitive gastrointestinal systems, it may cause symptoms such as nausea, vomiting, stomach pain, and loss of appetite. Long-term or high-dose use may lead to gastric mucosal erosion and ulcers, and severe cases may result in gastrointestinal bleeding. Gastrointestinal reactions should be closely monitored.
2. Bleeding Tendency
Aspirin inhibits platelet aggregation and prolongs clotting time. During use, symptoms such as gum bleeding, skin bruising, and nosebleeds may occur. If other anticoagulant medications are taken concurrently or if there is an existing coagulation disorder, the risk of bleeding increases. Be vigilant for any abnormal bleeding signs.
3. Allergic Reaction
Some individuals are sensitive to aspirin components and may experience skin allergic reactions such as rashes and hives. In severe cases, it may trigger asthma attacks or angioedema, presenting as difficulty breathing and facial swelling. If allergic symptoms occur, discontinue the medication immediately.
4. Liver and Kidney Function Damage
Long-term or excessive use of aspirin may cause damage to the liver and kidneys due to drug metabolites. Symptoms may include elevated transaminase levels, jaundice, reduced urine output, and edema. Regular monitoring of liver and kidney function indicators is necessary.
5. Salicylism
Excessive intake of aspirin can lead to accumulation of salicylic acid in the body, causing salicylism. Common symptoms include headache, dizziness, tinnitus, hearing loss, nausea, and vomiting. Severe cases may present with high fever and confusion. Strict adherence to the prescribed dosage is essential to avoid overdose.
When using aspirin, follow medical advice to determine dosage and duration of treatment; do not adjust the dosage on your own. Patients with conditions such as peptic ulcer disease, asthma, or impaired liver or kidney function should inform their doctor before use. If serious discomfort occurs during treatment, stop taking the medication immediately and seek medical attention. Long-term users should undergo regular check-ups of gastrointestinal, liver and kidney functions, and coagulation status to ensure safe medication use.