What medications are used for coronary heart disease?

Sep 15, 2025 Source: Cainiu Health

Dr. Ren Yi

Introduction

Coronary heart disease usually refers to coronary artery atherosclerotic heart disease. Under normal circumstances, patients with coronary artery atherosclerotic heart disease may follow medical advice to use medications such as aspirin enteric-coated tablets, clopidogrel bisulfate tablets, atorvastatin calcium tablets, metoprolol tartrate tablets, and isosorbide mononitrate sustained-release tablets for treatment. A detailed analysis is as follows:

　　Coronary heart disease usually refers to coronary atherosclerotic heart disease. Under normal circumstances, patients with coronary atherosclerotic heart disease may follow medical advice to use medications such as aspirin enteric-coated tablets, clopidogrel hydrogen sulfate tablets, atorvastatin calcium tablets, metoprolol tartrate tablets, and isosorbide mononitrate sustained-release tablets for treatment. Detailed analysis is as follows:

　　1. Aspirin Enteric-Coated Tablets

　　Aspirin inhibits platelet aggregation, prevents thrombus formation, and reduces the risk of thrombotic occlusion in the coronary arteries, thereby preventing angina attacks and myocardial infarction. It is the foundational medication for long-term antiplatelet therapy in patients with coronary atherosclerotic heart disease.

　　2. Clopidogrel Hydrogen Sulfate Tablets

　　As another antiplatelet drug, it works by blocking ADP receptors on the platelet surface, inhibiting platelet activation and aggregation. It is commonly used in patients who are intolerant to or have contraindications for aspirin, and can also be combined with aspirin during acute coronary syndrome episodes to enhance antiplatelet effects.

　　3. Atorvastatin Calcium Tablets

　　Belonging to the statin class of lipid-lowering drugs, it inhibits cholesterol synthesis in the liver, lowers total cholesterol and low-density lipoprotein cholesterol levels in the blood, stabilizes atherosclerotic plaques, delays plaque progression, and reduces the likelihood of acute cardiovascular events caused by plaque rupture.

　　4. Metoprolol Tartrate Tablets

　　As a beta-blocker, it slows heart rate, reduces myocardial contractility, decreases myocardial oxygen consumption, alleviates myocardial ischemia symptoms, and reduces the frequency and severity of angina attacks. Additionally, it can improve ventricular remodeling, protect cardiac function, and reduce long-term mortality risk in patients with coronary atherosclerotic heart disease.

　　5. Isosorbide Mononitrate Sustained-Release Tablets

　　A nitrate medication that dilates the coronary arteries, increases coronary blood flow, improves myocardial blood supply, and simultaneously dilates peripheral blood vessels, reducing cardiac workload and alleviating angina symptoms. It is suitable for long-term treatment and prevention of stable angina pectoris.

　　Maintaining healthy lifestyle habits is important. Avoid eating high-fat and high-cholesterol foods, such as organ meats and fried foods, as these may hinder recovery.

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