Is liver resection surgery highly risky?
Sep 26, 2025
Source: Cainiu Health
Dr. Gao Jun
Introduction
In general, the risk level of liver resection surgery should be comprehensively assessed based on the specific medical condition, extent of surgery, and the patient's overall health status. Prior to surgery, thorough preoperative evaluations are required to clearly determine liver function and tumor status. After surgery, close monitoring of vital signs and liver function parameters is essential, with prompt management of any abnormalities. Patients should follow medical advice regarding dietary adjustments and rehabilitation exercises.
Generally, the risk level of liver resection surgery depends on a comprehensive assessment of the specific medical condition, extent of surgery, and the patient's overall health. Detailed analysis is as follows:
If the patient’s condition is mild—for example, a small solitary hepatocellular carcinoma without severe liver cirrhosis—and only a small portion of liver tissue needs to be removed, particularly when the patient is relatively young with normal cardiac and pulmonary function and no underlying diseases, the risk of liver resection surgery is relatively low. The liver has strong regenerative capacity; after limited resection, recovery is usually rapid, and the probability of serious postoperative complications such as massive bleeding or liver failure is low. Most patients can recover smoothly.
However, if the patient has a more complex condition—such as a large tumor invading blood vessels, or coexisting severe cirrhosis and impaired liver function—requiring extensive liver resection, especially when combined with advanced age and comorbidities like diabetes or heart disease—the surgical risks significantly increase. Extensive liver removal may exceed the liver’s compensatory capacity, increasing the likelihood of postoperative liver failure. Additionally, pre-existing conditions raise the risk of complications such as infections or cardiovascular events, making the recovery process more challenging.
Prior to surgery, comprehensive evaluations should be completed to fully assess liver function and tumor status. After surgery, close monitoring of vital signs and liver function parameters is essential, with prompt intervention if abnormalities arise. Patients should follow medical advice regarding dietary adjustments and rehabilitation exercises, avoiding strenuous activities too early. Choosing an experienced medical team can also help reduce surgical risks to a certain extent.
