Is liver transplantation suitable for all patients with liver cancer?

Generally, liver transplantation is not suitable for all patients with liver cancer. A detailed analysis is as follows:

Liver transplantation is not appropriate for every liver cancer patient, as multiple factors must be comprehensively evaluated. If the tumor has already metastasized to distant sites, cancer cells may continue to spread after transplantation, making it ineffective as a treatment. If liver function is still relatively preserved and the tumor is small without vascular invasion, the disease can often be better controlled through surgical resection or other treatments, so transplantation does not need to be the first choice. Additionally, if a patient suffers from severe heart or lung diseases, active infections, or is elderly and physically frail, they may not tolerate the surgical trauma or the long-term immunosuppressive therapy required after transplantation, leading to a high risk of postoperative complications and potentially compromising quality of life.

In daily practice, individuals considering liver transplantation should undergo a comprehensive evaluation at a qualified hospital to determine whether they meet the indications. It is important to understand that lifelong immunosuppressive medications are required after transplantation, and patients should be prepared for long-term treatment. Before surgery, patients should cooperate with their doctors to manage underlying conditions and reduce surgical risks. After transplantation, strict adherence to medical instructions—including regular medication and follow-up exams—is essential to monitor liver function and detect any signs of rejection. During the waiting period for transplantation, patients should actively control the progression of liver cancer to avoid worsening of the condition and losing the opportunity for transplantation.