What causes pain on one side of the buttocks the day after drinking alcohol?

Oct 18, 2025 Source: Cainiu Health
Dr. Wang Lei
Introduction
In general, one-sided buttock pain the day after drinking alcohol may be caused by improper posture after drinking, alcohol's effect on muscle metabolism, sciatica, piriformis syndrome, or soft tissue infection in the buttocks. If discomfort occurs, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. In daily life, limit alcohol intake to avoid excessive consumption, and pay attention to maintaining proper posture after drinking.

Generally, pain in one side of the buttocks the day after drinking alcohol may be caused by improper posture after drinking, alcohol's impact on muscle metabolism, sciatica, piriformis syndrome, or soft tissue infection in the buttocks. If discomfort occurs, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. Specific causes are analyzed as follows:

1. Improper posture after drinking

Alcohol consumption can lead to impaired consciousness, and maintaining a lateral or sitting position for prolonged periods may result in continuous pressure on the muscles of one side of the buttocks, obstructing blood circulation and causing pain. Adjust sitting and sleeping postures to avoid prolonged pressure on one side of the buttocks; apply warm compresses with a heated towel to the painful area to promote local blood flow.

2. Alcohol's effect on muscle metabolism

Lactic acid produced during alcohol metabolism may accumulate in the buttock muscles, while alcohol also inhibits muscle recovery, leading to soreness on one side of the buttocks. Drink plenty of warm water to accelerate the elimination of alcohol and lactic acid, engage in light walking to activate the buttock muscles, and avoid strenuous exercise that could worsen discomfort.

3. Sciatica

Alcohol may irritate the sciatic nerve or exacerbate pre-existing inflammation, resulting in radiating pain on one side of the buttocks, often accompanied by leg numbness. Under medical guidance, medications such as mecobalamin tablets, vitamin B1 tablets, or ibuprofen sustained-release capsules may be taken. Avoid prolonged sitting and choose soft, supportive seating to reduce nerve compression.

4. Piriformis syndrome

Alcohol may trigger spasms of the piriformis muscle, compressing the sciatic nerve and causing pain on one side of the buttocks, which worsens with movement. Under medical supervision, medications such as eperisone hydrochloride tablets, celecoxib capsules, or diclofenac sodium sustained-release tablets may be used. In severe cases, piriformis muscle release surgery may be required; after surgery, avoid strenuous physical activity.

5. Soft tissue infection in the buttocks

After drinking, immune function may decline, making minor existing wounds or hair follicles in the buttocks susceptible to bacterial infection, leading to localized pain and swelling. Under medical guidance, antibiotics such as amoxicillin capsules, cefuroxime axetil tablets, or levofloxacin tablets may be prescribed. If an abscess forms, incision and drainage surgery may be necessary; postoperative care should include keeping the wound clean and dry.

In daily life, limit alcohol intake to avoid excessive consumption, maintain proper posture after drinking, engage in regular physical activity to prevent prolonged sitting or lying down, keep the skin of the buttocks clean to prevent infection, and for individuals with underlying nerve or muscular conditions, undergo regular follow-up evaluations to minimize potential triggers.

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