Can appendicitis affect gastric perforation?
In general, whether appendicitis affects gastric perforation depends on the severity of the condition. Ordinary acute or chronic appendicitis usually does not directly impact gastric perforation. However, if appendicitis progresses to severe suppurative infection or perforation leading to diffuse peritonitis, it may indirectly increase the risk of gastric injury, although it does not directly cause gastric perforation. The detailed analysis is as follows:

During an ordinary attack of appendicitis, inflammation is confined to the appendix area and mainly manifests as right lower abdominal pain, nausea, and other symptoms. The lesion does not involve the stomach, so there is no direct association with gastric perforation. Gastric perforation is mostly caused by factors such as peptic ulcers or gastric trauma. Since the pathogenic mechanisms of the two conditions are different, ordinary appendicitis does not affect the occurrence of gastric perforation.
When appendicitis becomes severe, with abscess formation or perforation of the appendix, bacteria and pus from the intestines can spread into the abdominal cavity, causing diffuse peritonitis. This inflammatory irritation may affect multiple organs in the abdominal cavity, including the stomach. Although it does not directly lead to perforation of the gastric wall, it may exacerbate mucosal damage in the stomach or trigger discomfort on the basis of pre-existing gastric diseases, thereby increasing the risk of gastric lesions.
To reduce the risk of complications from appendicitis, individuals should seek prompt medical evaluation for persistent right lower abdominal pain, fever, or similar symptoms to ensure timely diagnosis and prevent disease progression. During illness, maintain a light diet, avoid strenuous exercise, and reduce abdominal strain.