Is an empty sella a tumor?
In most cases, empty sella is not caused by a tumor; however, it may be associated with tumors if induced by tumor compression or invasion. If there are concerns, early medical consultation is recommended. Detailed analysis is as follows:

Most non-tumorous cases arise from congenital abnormalities in the development of the sella turcica, or from acquired pituitary atrophy and changes in cerebrospinal fluid (CSF) pressure, leading to CSF filling the sella and forming an empty appearance. These types of empty sella do not involve tumor cells. Patients may remain asymptomatic and the condition is often discovered incidentally during routine examinations. No specific treatment is required—regular follow-up monitoring is sufficient.
In rare cases related to tumors, the empty sella phenomenon may result from tumors such as pituitary adenomas or craniopharyngiomas compressing pituitary tissue, or from reduced pituitary volume following tumor treatment, creating an empty space within the sella. Alternatively, direct tumor invasion into the sellar region may alter the sella's structure and lead to cavity formation. In such instances, management should be integrated with the overall tumor treatment plan to prevent disease progression.
After detecting an empty sella, further evaluation is necessary to determine the underlying cause. Regular monitoring of the sella and pituitary function is essential. Prompt medical attention should be sought if symptoms such as headaches or visual deterioration occur, and subsequent interventions should follow professional medical advice.