Who should not undergo appendectomy surgery

Nov 05, 2025 Source: Cainiu Health
Dr. Wang Lei
Introduction
Groups unsuitable for appendectomy mainly include individuals with severe cardiopulmonary diseases, those in an active phase of specific infections, patients with coagulation disorders, those with advanced malignant tumors, and elderly individuals who are extremely frail. These individuals should receive standardized conservative treatment under medical supervision, such as using antibiotics to control inflammation and intravenous fluid therapy to maintain electrolyte balance.

Generally, individuals unsuitable for appendectomy mainly include those with severe cardiopulmonary diseases, those in a special infectious phase, those with coagulation disorders, patients with advanced malignant tumors, and elderly individuals who are extremely frail. The detailed analysis is as follows:

1. Individuals with severe cardiopulmonary diseases: Patients suffering from severe heart failure, acute myocardial infarction, severe pneumonia, or respiratory failure may not tolerate the trauma of surgery and anesthesia stimulation. Life-threatening events such as cardiac arrest or respiratory failure may occur during the operation.

2. Individuals in a special infectious phase: When a patient is experiencing systemic severe infections such as sepsis or bacteremia, or has an acute infection near the surgical site, surgery could lead to the spread of infection and worsen the condition. Systemic infection should first be controlled, and surgery considered only after the infection stabilizes.

3. Individuals with coagulation disorders: Patients with hemophilia, severe liver disease, or those taking long-term anticoagulant medications that cannot be discontinued have abnormal clotting functions. They are at high risk of uncontrollable bleeding during surgery and poor wound healing afterward, making them generally unsuitable candidates for appendectomy.

4. Patients with advanced malignant tumors: In patients with advanced cancer, bodily functions are severely compromised and immunity is extremely low. Surgical trauma may further weaken resistance, leading to difficult postoperative recovery and potentially triggering other complications.

5. Elderly individuals who are extremely frail: Patients over 80 years old, especially those with multiple chronic conditions, long-term bedridden status, and extreme physical weakness, have poor tolerance to surgery. They face a high risk of postoperative complications such as pulmonary infections and thrombosis. Conservative treatment is usually preferred, with surgery considered only if conservative management fails.

Individuals unsuitable for appendectomy should receive standardized conservative treatment under medical guidance, including antibiotic use to control inflammation and intravenous fluid therapy to maintain electrolyte balance.

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