Is Sjögren's syndrome a death sentence?

Nov 07, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Most patients experience a slow disease progression, presenting only with localized glandular symptoms such as dry mouth and dry eyes. With standardized interventions and long-term management, symptoms can be effectively controlled, disease progression delayed, and normal life expectancy and quality of life preserved. A minority of patients may develop internal organ involvement or severe systemic complications. However, early detection, precise treatment, and regular monitoring can effectively control disease progression.

Generally, Sjögren's syndrome is not an incurable disease. It is a chronic autoimmune disorder that can be prevented and managed effectively, and it does not directly lead to death. If any abnormalities occur, timely medical consultation is recommended. Detailed analysis is as follows:

Most patients experience slow disease progression, with symptoms limited to local glandular manifestations such as dry mouth and dry eyes. With standardized interventions and long-term management, symptoms can be effectively controlled, disease progression delayed, and normal life expectancy and quality of life maintained, allowing for long-term stable survival.

A minority of patients may develop internal organ involvement or severe systemic damage. Without timely intervention, complications may arise. However, even in these cases, early detection, precise treatment, and regular monitoring can effectively control disease progression and reduce adverse risks.

After diagnosis, it is essential to follow medical advice for regular treatment and periodic follow-up evaluations to monitor disease changes and avoid delays in intervention.

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