Can vitamin C, vitamin E, and niacin be taken long-term?
Generally speaking, whether vitamin C, vitamin E, and niacin can be taken long-term should be determined based on dosage, individual health status, and the purpose of use. The specific distinctions are as follows:

If taken at the recommended daily dose, and the individual is in good health without related medical conditions, and supplementation is needed due to inadequate dietary intake or special physiological stages (e.g., pregnancy, aging), long-term use may be appropriate under professional guidance. At such doses, these vitamins meet basic bodily needs, help maintain normal physiological functions, and are unlikely to cause adverse effects, making them suitable for routine nutritional supplementation.
Long-term use is not recommended if doses exceed recommendations, if the individual has pre-existing medical conditions, or if supplements are taken without a clear need. Excessive intake increases metabolic burden on the body and may lead to various adverse effects—for example, excess vitamin C may cause diarrhea, too much vitamin E may impair blood clotting, and excessive niacin may result in skin flushing or liver damage, posing risks to health.
When supplementing daily, it is important to strictly adhere to recommended dosages and avoid self-adjusting upward; monitor your body's response regularly and discontinue use immediately if any adverse reactions occur, seeking medical advice promptly; prioritize obtaining nutrients through a balanced diet by consuming more fresh fruits, vegetables, nuts, and other foods rich in these vitamins; individuals with underlying health conditions should inform their doctor before starting supplementation to ensure safety and minimize health risks.