Can depression be detected through instrumental examinations?
Generally speaking, depression is a mental disorder primarily characterized by low mood. Currently, there is no way to directly diagnose depression solely through instrumental examinations; diagnosis requires a comprehensive evaluation based on multiple factors. If you experience related symptoms or suspect you may have depression, it is recommended to seek medical help promptly. The specific analysis is as follows:

The core issue of depression lies in imbalances of brain neurotransmitters and abnormal neural circuit function. These changes are difficult to quantify clearly using current medical instruments. The manifestations of the disease—such as depressed mood, reduced interest, and slowed thinking—are primarily subjective experiences. Accompanying symptoms like changes in sleep and appetite lack specificity. Instruments can only help rule out organic causes such as brain tumors or thyroid dysfunction, but cannot capture the complex emotional and cognitive abnormalities. Therefore, they cannot serve as direct diagnostic evidence. Diagnosis must be made by integrating symptom presentation, duration of illness, and patient history.
If emotional disturbances persist for more than two weeks, individuals should promptly consult a psychiatrist or mental health professional, avoiding self-diagnosis that could delay timely intervention. Family members and friends should offer understanding and companionship, refraining from dismissing the patient's feelings. Patients themselves should actively communicate their inner state and cooperate with doctors during thorough clinical interviews. After diagnosis, treatment should be followed strictly according to medical advice; interventions should not be discontinued simply because symptoms temporarily improve. In daily life, regular physical activity and participation in enjoyable activities can assist in emotional regulation, helping maintain a stable routine.