How long after an injection for appendicitis will the pain go away?

Nov 14, 2025 Source: Cainiu Health

Dr. Wang Lei

Introduction

In general, the time it takes for pain to subside after injection treatment for appendicitis varies from person to person. For simple appendicitis, pain typically significantly decreases within 1–3 days; for suppurative or gangrenous appendicitis, it may take 3–5 days, and in some cases even longer. If pain does not improve after 3–5 days of injections, or if symptoms such as worsening pain or fever develop, this may indicate inadequate control of the inflammation.

In general, the time it takes for pain to subside after injection treatment for appendicitis varies from person to person. For simple appendicitis, pain typically begins to significantly decrease within 1–3 days; for suppurative or gangrenous appendicitis, it may take 3–5 days, and in some cases even longer. A detailed analysis is as follows:

Injection treatment primarily involves intravenous antibiotics to control inflammation, and the speed of pain relief is directly related to the severity of the inflammation. In simple appendicitis, where inflammation is mild, antibiotics can quickly suppress bacterial growth and reduce congestion and edema in the appendix. Most patients begin to experience pain relief within one day of starting treatment, with symptoms largely disappearing by around three days. However, if the inflammation has progressed to a suppurative stage with significant swelling of the appendix, pain relief will be relatively slower, often requiring more than three days before noticeable improvement occurs. Nursing care during treatment also affects the pace of pain relief. Patients should strictly remain in bed and avoid strenuous activity that could further irritate the appendix. Diet should consist mainly of liquids or semi-liquids to reduce gastrointestinal burden.

If pain does not improve after 3–5 days of injections, or if symptoms such as increased pain or fever develop, this may indicate inadequate control of inflammation. In such cases, the treatment plan should be adjusted promptly, and surgical intervention may become necessary. Close monitoring of symptom changes throughout treatment and active cooperation with medical staff guidance are essential.

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Is acute gangrenous appendicitis serious?

In general, acute gangrenous appendicitis is a severe form of appendicitis in which the blood supply to the appendix is compromised, leading to tissue necrosis. If experiencing discomfort or symptoms, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. Immediate medical attention is required if symptoms such as persistent severe abdominal pain, high fever, nausea, and vomiting occur; do not self-administer painkillers, as this may mask the condition. After seeking medical care, patients should actively cooperate with diagnostic examinations.

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Can intravenous therapy cure appendicitis?

In early-stage simple appendicitis, intravenous fluids may help control the condition. However, if the appendix becomes purulent, perforated, or gangrenous, intravenous therapy cannot provide a definitive cure and timely surgical treatment is required. Intravenous fluids primarily work by administering antibiotics to combat infection and reduce inflammation, but they cannot resolve underlying issues such as appendiceal obstruction. If symptoms such as worsening abdominal pain, high fever, or vomiting occur, immediate medical attention is recommended.

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Can appendicitis recur after intravenous treatment?

If appendicitis is a simple inflammation without abscess formation or perforation of the appendix, timely administration of adequate intravenous antibiotics can lead to complete resolution of the inflammation, and appendix function gradually returns to normal. With regular diet and avoidance of strenuous exercise, the recurrence rate after intravenous treatment is low, and most patients can remain stable for a long period.