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How to discontinue venlafaxine hydrochloride sustained-release capsules

Nov 20, 2025 Source: Cainiu Health
Dr. Huang Yuhong
Introduction
If the condition is stable and the doctor's assessment indicates eligibility for discontinuation, an individualized tapering plan will be developed based on dosage and duration of medication use—for example, reducing a fixed dose weekly—while closely monitoring the body's response. Gradual dose reduction allows the body time to adjust, minimizing the likelihood of withdrawal symptoms such as dizziness, anxiety, and insomnia, thereby ensuring a smooth and safe discontinuation process.

Under normal circumstances, venlafaxine hydrochloride extended-release capsules should be gradually tapered off under a doctor's guidance. Do not discontinue the medication abruptly on your own, and promptly communicate with your doctor if any discomfort occurs. If you have concerns, it is recommended to seek medical advice in advance. Detailed explanations are as follows:

If your condition is stable and your doctor determines that discontinuation is appropriate, an individualized tapering plan will be developed based on your dosage and duration of treatment—for example, reducing the dose by a fixed amount each week—while closely monitoring your physical response. Gradual tapering allows your body time to adjust, reducing the likelihood of withdrawal symptoms such as dizziness, anxiety, and insomnia, thereby ensuring a smooth discontinuation process.

Discontinuing the medication suddenly on your own or arbitrarily accelerating the tapering speed without following medical advice may prevent your body from adapting quickly to changes in drug levels. This can easily trigger withdrawal reactions, including nausea, palpitations, mood swings, and difficulty concentrating. It may also lead to relapse or worsening of original symptoms, compromise prior treatment outcomes, and increase the difficulty of subsequent management.

During treatment with venlafaxine hydrochloride extended-release capsules, never decide independently to stop taking the medication or alter the dosage. If you are considering discontinuation, consult your treating physician immediately. Strictly adhere to medical instructions throughout the tapering process and promptly report any adverse effects to ensure safety during both treatment and discontinuation.

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