Does Fule Decoction treat depression?

Nov 21, 2025 Source: Cainiu Health

Dr. Sun Lianqing

Introduction

Fule Decoction can be used as an adjunctive treatment for depression, but it is not a first-line core therapeutic medication. Based on the TCM principle of syndrome differentiation and treatment, it helps regulate depression with specific syndrome patterns, but cannot replace standardized Western medical treatments or professional psychological interventions. If depressive symptoms persistently worsen, including low mood and loss of interest lasting more than two weeks, prompt medical consultation is recommended.

　　Fule Decoction can be used as an adjunctive treatment for depression, but it is not a first-line core medication. Based on the principles of TCM syndrome differentiation and treatment, it helps regulate depression with specific syndrome patterns, but cannot replace standardized Western medical treatments or professional psychological interventions. If depressive symptoms persist or worsen, such as low mood and loss of interest lasting more than two weeks, prompt medical attention is recommended.

　　Fule Decoction typically consists of traditional Chinese herbs such as Bupleurum (Chai Hu), Curcuma (Yu Jin), Angelica sinensis (Dang Gui), and Poria (Fu Ling), which are known for soothing the liver, regulating qi, strengthening the spleen, and nourishing the heart. In traditional Chinese medicine, depression is associated with stagnation of liver qi and insufficient nourishment of the heart spirit. The primary effects of this formula are to soothe the liver and relieve depression, regulate qi and promote blood circulation, and calm the mind. It may help alleviate symptoms such as emotional depression, chest tightness, frequent sighing, insomnia, and vivid dreams.

　　This prescription is suitable for depression characterized by liver qi stagnation with spleen deficiency and qi stagnation with blood stasis. It may assist in emotional regulation for patients with mild to moderate depression. However, for severe depression or cases involving suicidal ideation, its efficacy as a standalone treatment is limited, and comprehensive interventions—such as antidepressant medications and cognitive behavioral therapy—are necessary.

　　While taking Fule Decoction, it is important to maintain a positive mood and avoid emotional stress, follow a regular sleep schedule without staying up late, eat a light and easily digestible diet, and avoid spicy and greasy foods. Engaging moderately in gentle activities such as walking or meditation can also support emotional recovery and enhance the therapeutic effect.

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