Can people with depression have their pupils dilated?
Nov 21, 2025
Source: Cainiu Health
Dr. Zhang Baohua
Introduction
Dilation primarily affects the eye, using medication to enlarge the pupil for procedures such as refraction or fundus examination. It usually does not directly influence mood or exacerbate symptoms of depression. If a patient has normal ocular structures, no glaucoma, abnormal intraocular pressure, or active inflammation, and has not recently taken medications that may affect pupillary response, routine dilation can be performed.
Generally, whether patients with depression can undergo pupil dilation depends on their eye health status, and there is no absolute contraindication. If any abnormalities occur, prompt medical attention is recommended. Detailed analysis is as follows:
Pupil dilation primarily affects the eyes, using medication to enlarge the pupils for procedures such as refraction testing or fundus examination, and typically does not directly impact mood or worsen depressive symptoms. If the patient has normal ocular structure, no glaucoma, abnormal intraocular pressure, or active inflammation, and has not recently taken medications that may affect pupillary response, routine pupil dilation can be performed.
If the patient has uncontrolled glaucoma, elevated intraocular pressure above normal levels, or is in the recovery phase of an eye infection or trauma, pupil dilation may trigger increased intraocular pressure or exacerbate inflammation, and should therefore be avoided. Additionally, individuals allergic to components of the mydriatic agents must not use them.
After pupil dilation, temporary symptoms such as light sensitivity and blurred near vision may occur. Exposure to bright light should be avoided, and wearing a sun hat or sunglasses when outdoors is recommended. If abnormal symptoms such as eye pain, headache, or sudden vision loss occur, the procedure should be stopped immediately and medical help sought.
