Dextran 40 Glucose Injection: Functions and Effects
Nov 24, 2025
Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Dextran 40 Glucose Injection functions to expand blood volume, improve microcirculation, reduce blood viscosity, prevent thrombus formation, and assist in the treatment of shock. It is commonly used in clinical practice for the management of vascular-related diseases. If symptoms such as rash, difficulty breathing, or bleeding tendency occur after administration, prompt medical attention is recommended.
Dextran 40 Glucose Injection is used to expand blood volume, improve microcirculation, reduce blood viscosity, prevent thrombosis, and assist in the treatment of shock. It is commonly used clinically for treating vascular-related diseases. If symptoms such as rash, difficulty breathing, or bleeding tendencies occur after administration, prompt medical attention is recommended.
1. **Expand Blood Volume:** By increasing plasma colloid osmotic pressure, it draws fluid from tissue spaces into the bloodstream, rapidly replenishing blood volume. It is suitable for hypovolemia caused by hemorrhage or dehydration, helping alleviate symptoms such as dizziness and fatigue.
2. **Improve Microcirculation:** It reduces blood viscosity and inhibits platelet aggregation, thereby accelerating blood flow in the microcirculation and improving tissue hypoxia. It is often used as adjunctive therapy for diseases associated with microcirculatory disorders.
3. **Reduce Blood Viscosity:** It dilutes concentrations of components such as red blood cells in the blood, reducing resistance to blood flow. It is suitable for patients with hyperviscosity syndrome and helps lower the risk of thrombosis.
4. **Prevent Thrombosis:** By inhibiting platelet adhesion and aggregation, it reduces the likelihood of thrombus formation. It can be used for prevention in high-risk individuals or as adjunctive treatment for thrombotic diseases.
5. **Assist in Shock Treatment:** Rapidly expands blood volume while improving microcirculation, buying critical time for the resuscitation of shock patients. It is indicated as adjunctive therapy for hypovolemic shock, septic shock, and similar conditions.
During treatment, infusion rate must be controlled according to medical instructions to avoid adverse reactions due to overly rapid administration. Vital signs such as blood pressure and heart rate should be monitored. A light diet is recommended, avoiding high-fat and high-sugar foods, to support therapeutic efficacy and promote recovery.
