Can I take aspirin after receiving an adenovirus vector vaccine?

Generally, after receiving an adenovirus vector vaccine, individuals with underlying medical conditions requiring long-term aspirin use may continue taking it as directed by their physician. However, caution is advised if aspirin is intended for temporary use or if there is a tendency toward bleeding. If in doubt, it is recommended to consult a healthcare provider in advance. Detailed analysis is as follows:

If a person is already on regular aspirin therapy due to cardiovascular or cerebrovascular diseases, discontinuing the medication without guidance after vaccination may increase the risk of complications related to their underlying condition. In such cases, continuing the prescribed dose under medical evaluation is acceptable. Aspirin primarily functions to inhibit platelet aggregation, and currently, there is no evidence indicating any interaction between aspirin and components of adenovirus vector vaccines, nor does it interfere with the immune response induced by the vaccine.

For individuals without clear underlying conditions who are considering short-term aspirin use for mild symptoms such as headache or fever, or those with a predisposition to bleeding, temporary avoidance of aspirin is recommended. Redness and swelling at the injection site may occur after vaccination, and aspirin's anticoagulant effect could increase the risk of local bleeding or swelling. Mild discomfort can often be relieved through physical measures, so there is no need to rush into medication. If aspirin use is necessary, dosage and timing should be determined under a doctor’s assessment.

Before taking aspirin, inform your doctor about your recent vaccination and overall health status so that a safe and appropriate medication plan can be established. During treatment, closely monitor the injection site and general bodily reactions. Seek immediate medical attention if abnormal bleeding or other adverse symptoms occur.