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What causes the sensation of insects crawling on the lower leg?

Nov 28, 2025 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
In general, the sensation of insects crawling on the lower leg may be caused by dry or dehydrated skin, clothing irritation and friction, peripheral neuropathy, restless legs syndrome, varicose veins, or other reasons. If symptoms occur frequently, it is recommended to seek timely medical evaluation at a正规 hospital. In daily life, maintain moisture in the skin of the lower legs, choose comfortable clothing, control blood sugar levels, and maintain a balanced diet.

Generally, the sensation of insects crawling on the lower leg may be caused by dry or dehydrated skin, clothing irritation and friction, peripheral neuropathy, restless legs syndrome, varicose veins, or other reasons. If symptoms occur frequently, it is recommended to seek timely medical attention at a正规 hospital. Specific analyses are as follows:

1. Dry and dehydrated skin: In dry climates or with insufficient water intake, the stratum corneum of the skin on the lower leg may become dehydrated and cracked, stimulating nerve endings and causing abnormal sensations. Apply a gentle moisturizing lotion daily, focusing on care for the lower legs. Use a humidifier indoors and ensure adequate daily fluid intake.

2. Clothing irritation and friction: Rough-textured or overly tight clothing can repeatedly rub against the skin of the lower leg, compressing nerve endings and causing discomfort. Switch to loose cotton clothing, avoid direct contact of synthetic fibers or wool with the skin, and use non-irritating detergents when laundering clothes.

3. Peripheral neuropathy: Nerve damage caused by conditions such as diabetes or nutritional deficiencies can lead to abnormal nerve conduction in the lower leg, resulting in a crawling sensation. Medications such as mecobalamin tablets, vitamin B1 tablets, and epalrestat tablets may be taken under medical guidance. Actively manage underlying diseases and consume foods rich in B-complex vitamins.

4. Restless legs syndrome: This condition is associated with abnormal dopamine function. A crawling sensation in the lower leg occurs during rest and improves with movement. Medications such as pramipexole tablets, ropinirole tablets, or gabapentin capsules may be used under medical supervision. Soaking feet in warm water before bedtime and avoiding caffeine intake are also recommended.

5. Varicose veins: Damage to venous valve function leads to impaired blood return and venous congestion in the lower leg, which stimulates the skin. Medications such as micronized purified flavonoid fraction (MPFF) tablets, diosmin tablets, or calcium dobesilate capsules may be used according to medical advice. In severe cases, surgical procedures such as high ligation and stripping of the great saphenous vein may be required. Avoid prolonged standing.

In daily life, maintain adequate moisture of the skin on the lower legs; wear comfortable clothing; control blood glucose levels and maintain a balanced diet; follow a regular sleep schedule and avoid excessive fatigue; engage in moderate exercise to promote lower limb blood circulation and reduce discomfort.

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