Is it normal to experience itching after receiving an injection of levofloxacin?
Nov 28, 2025
Source: Cainiu Health
Dr. Liu Wenmin
Introduction
Mild and transient itching after injection of levofloxacin may be due to drug irritation. However, if the itching persists or worsens, or is accompanied by skin rash, hives, facial swelling, or even symptoms such as difficulty breathing, dizziness, or nausea, it is likely an allergic reaction to the drug—an abnormal condition that requires immediate notification of medical staff. The medication should be discontinued promptly, and anti-allergic treatment should be administered to prevent further worsening of the allergic reaction.
Generally, mild and transient itching after injection of levofloxacin may be due to drug irritation. However, if it is accompanied by rash or difficulty breathing, it is considered abnormal. In such cases, prompt medical attention is recommended. The detailed analysis is as follows:
If only mild localized itching occurs without other discomfort and resolves spontaneously within a short time, it is usually due to minor irritation of the skin at the injection site. This is a relatively common mild reaction that typically requires no special treatment. Continue monitoring your condition and avoid scratching the injection area.
If the itching persists or worsens, or is accompanied by skin redness, rashes, hives, facial swelling, or even symptoms such as difficulty breathing, dizziness, or nausea, it is likely an allergic reaction to the medication—an abnormal condition. Immediately inform healthcare providers, discontinue the drug, and receive anti-allergic treatment to prevent further worsening of the allergic response.
Close monitoring of bodily reactions is essential during levofloxacin injection. Report any discomfort promptly; patients with a history of drug allergy should inform healthcare providers before injection. Do not attempt to assess symptom severity on your own, to avoid delays in timely management.
