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What could be the reason for a painless lump appearing on the lower right side, and what should I do about it?

Nov 29, 2025 Source: Cainiu Health
Dr. Li Feng
Introduction
A painless bump on the lower right side may be caused by blocked sebaceous glands, friction irritation, vestibular gland cyst, genital warts (condyloma acuminata), or pseudowarts. If the bump persists or changes in appearance, it is advisable to seek timely medical evaluation at a reputable hospital. In daily life, maintain local cleanliness and dryness, wear breathable clothing, avoid unhygienic sexual practices, and take proper protective measures.

A painless bump on the lower right side may be caused by blocked sebaceous glands, friction irritation, Bartholin's cyst, genital warts (condyloma acuminata), or pseudowarts. If the bump persists or changes in appearance, it is recommended to seek timely medical evaluation at a正规 hospital. Detailed analysis is as follows:

1. Blocked Sebaceous Glands

Excessive sebum production in the local area can lead to duct blockage and the formation of retention cysts, presenting as soft, smooth lumps. Maintain good local hygiene, wear breathable and loose clothing, avoid squeezing, clean daily with warm water, and keep the area dry.

2. Friction Irritation

Long-term wearing of tight clothing or repeated friction may cause local skin tissue hyperplasia, forming firm-textured bumps. Switch to cotton, loose-fitting clothes, reduce local friction, avoid prolonged sitting, and stand up periodically to promote local blood circulation.

3. Bartholin's Cyst

Blockage of the Bartholin's gland duct leads to accumulation of secretions and cyst formation, usually appearing as a unilateral, oval lump. Follow medical advice for potassium permanganate sitz baths and oral administration of cefuroxime axetil tablets, amoxicillin capsules, or metronidazole tablets. Large cysts may require marsupialization surgery.

4. Genital Warts (Condyloma Acuminata)

Caused by human papillomavirus (HPV) infection, these bumps have a rough surface resembling cauliflower. Treatment under medical supervision includes topical imiquimod cream, oral transfer factor solution or thymopeptide enteric-coated tablets, and possible laser ablation.

5. Pseudowarts (Vulvar Papillomatosis)

Triggered by vaginal discharge irritation or poor local hygiene, these appear as small bumps arranged like fish roe. Maintain good vulvar hygiene using洁尔阴 (Jieeryin) antiseptic wash. Use recombinant human interferon α2b gel or clotrimazole cream topically as prescribed, and avoid unhygienic contact.

In daily life, maintain cleanliness and dryness of the affected area; wear breathable clothing; avoid unsafe sexual practices and use proper protection; undergo regular gynecological checkups and address any abnormalities promptly; reduce intake of spicy and irritating foods to maintain endocrine balance.

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