What medication should be taken to reduce the virus in cases of high hepatitis B viral load?

Dec 01, 2025 Source: Cainiu Health
Dr. Gao Jun
Introduction
For high levels of hepatitis B virus, antiviral medications are required. Commonly used drugs include entecavir tablets, tenofovir disoproxil fumarate capsules, tenofovir alafenamide tablets, lamivudine tablets, and adefovir dipivoxil tablets. The choice of medication should be made according to the patient's condition, renal function, and other factors, under medical guidance. If hepatitis B viral load continues to rise or is accompanied by abnormal liver function, prompt medical evaluation and standardized treatment are recommended.

Hepatitis B virus with high viral load requires antiviral drug treatment. Commonly used medications include entecavir tablets, tenofovir disoproxil fumarate capsules, tenofovir alafenamide tablets, lamivudine tablets, and adefovir dipivoxil tablets. The choice should be made according to the patient's condition, renal function, and other factors under medical guidance. If hepatitis B viral load continues to rise or is accompanied by abnormal liver function, timely medical evaluation and standardized treatment are recommended.

1. Entecavir tablets: A guanine nucleoside analog that potently inhibits hepatitis B virus replication, with a low rate of drug resistance. It is suitable for patients with chronic hepatitis B and shows good efficacy and tolerability, especially in treatment-naive patients.

2. Tenofovir disoproxil fumarate capsules: A nucleotide reverse transcriptase inhibitor that effectively suppresses the replication of hepatitis B virus. It has strong antiviral activity and is indicated for adults and adolescents aged 12 years and older. Renal function should be monitored during treatment.

3. Tenofovir alafenamide tablets: A prodrug of tenofovir, it has comparable antiviral efficacy to tenofovir disoproxil but offers improved safety profiles regarding kidneys and bones. It is particularly suitable for patients with renal insufficiency or those at risk of osteoporosis.

4. Lamivudine tablets: One of the earlier nucleoside drugs used for hepatitis B antiviral therapy, it can inhibit viral replication and slow disease progression. However, long-term use is associated with a high risk of drug resistance, so it is often used as part of combination therapy or as an alternative option.

5. Adefovir dipivoxil tablets: Works by inhibiting hepatitis B virus DNA polymerase and is suitable for chronic hepatitis B patients requiring long-term treatment. It has relatively low resistance rates, but renal function should be regularly monitored.

In daily life, maintain a light diet and avoid spicy, greasy foods and alcohol; follow a regular sleep schedule and avoid staying up late or overexertion; engage in moderate, gentle exercise to strengthen physical health; strictly adhere to prescribed medication without self-adjustment; and undergo regular monitoring of viral load and liver function.

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