What does it mean when AST/ALT 1.7 is elevated?
Dec 03, 2025
Source: Cainiu Health
Dr. Huang Yuhong
Introduction
If both AST and ALT levels are within the normal reference range, and only the AST/ALT ratio is 1.7, this situation is generally not a cause for concern. A slightly elevated ratio may result from individual metabolic differences or short-term irregular lifestyle factors prior to testing (such as staying up late or alcohol consumption), and does not indicate significant liver damage. After adjusting lifestyle habits, follow-up testing usually shows normalization of the ratio.
Generally, an AST/ALT ratio of 1.7 should be interpreted in conjunction with the individual values of these two enzymes. If both enzyme levels are within normal ranges, there is usually no cause for concern. However, if either value is abnormal, it may indicate potential liver problems. In case of concerns, it is recommended to seek medical advice promptly. Detailed analysis is as follows:
If both AST and ALT levels fall within their respective normal reference ranges and only the AST/ALT ratio is 1.7, this situation is generally not worrisome. A slightly elevated ratio may result from individual metabolic differences or short-term lifestyle factors prior to testing (such as staying up late or alcohol consumption), and does not necessarily reflect substantial liver damage. The ratio often returns to normal upon retesting after improving lifestyle habits.
If the AST level alone exceeds the upper limit of normal, or the ALT level falls below the lower limit of normal—leading to an AST/ALT ratio of 1.7—this scenario warrants caution. Elevated AST is commonly seen in conditions involving hepatocyte mitochondrial injury or myocardial damage, while low ALT may be associated with nutritional status. Further evaluation, including a complete liver function panel and abdominal ultrasound of the liver and biliary system, is recommended to determine whether any underlying disease exists.
Upon finding an elevated AST/ALT ratio of 1.7, first review the individual enzyme values. If both are normal, consider adjusting sleep patterns and retest later. If either enzyme is abnormal, seek timely medical evaluation to identify the cause. In daily life, avoid excessive alcohol consumption and drug misuse, maintain a regular diet, and reduce metabolic burden on the liver.
