How to treat anemia in rheumatoid arthritis
Dec 10, 2025
Source: Cainiu Health
Dr. Yang Tiesheng
Introduction
Treatment methods for anemia in patients with rheumatoid arthritis include controlling the underlying disease, iron supplementation, vitamin B12 and folic acid supplementation, use of erythropoietin, and adjusting dietary structure. Treatment should be standardized based on the type of anemia and severity of the condition. If anemia symptoms are significant or accompanied by dizziness and palpitations, prompt medical evaluation is recommended to determine the underlying cause.
Anemia in patients with rheumatoid arthritis can be managed through controlling the underlying disease, iron supplementation, vitamin B12 and folic acid supplementation, use of erythropoiesis-stimulating agents, dietary adjustments, and other approaches. Treatment should be standardized based on the type of anemia and severity of the condition. If anemia symptoms are significant or accompanied by dizziness and palpitations, prompt medical evaluation is recommended to determine the cause.
1. Control the underlying disease: Anemia associated with rheumatoid arthritis is often related to chronic inflammation. Proper use of anti-rheumatic drugs to control joint inflammation helps reduce the inhibitory effects of inflammatory factors on hematopoiesis, thereby improving anemia at its root.
2. Iron supplementation: For iron-deficiency anemia, oral or injectable iron supplements should be taken under medical guidance to provide raw materials for blood formation. Avoid concomitant use with medications that interfere with iron absorption to enhance iron utilization.
3. Vitamin B12 and folic acid supplementation: For megaloblastic anemia, supplementing vitamin B12 and folic acid corrects deficiencies in hematopoietic nutrients, supports normal red blood cell production, and alleviates symptoms related to anemia.
4. Use of erythropoiesis-stimulating agents: In cases of anemia of chronic disease or renal anemia, erythropoiesis-stimulating agents may be used after physician evaluation to stimulate bone marrow function, increase red blood cell count, and improve anemic status.
5. Dietary adjustment: Consume more foods rich in iron, vitamin B12, and folic acid—such as red meat, animal liver, and fresh fruits and vegetables—to ensure balanced nutrition and support hematopoiesis, complementing pharmacological treatments.
During treatment, regular blood tests should be performed to monitor changes in anemia indicators; avoid excessive fatigue and ensure adequate sleep; engage in moderate, gentle exercise to promote circulation; and strictly follow medical instructions regarding medication without self-adjusting dosage or discontinuing treatment.
